Protein Information: D(2) dopamine receptor
Cannonical Uniprot Accesion Number: P14416
10 20 30 40 50 MDPLNLSWYD DDLERQNWSR PFNGSDGKAD RPHYNYYATL LTLLIAVIVF 60 70 80 90 100 GNVLVCMAVS REKALQTTTN YLIVSLAVAD LLVATLVMPW VVYLEVVGEW 110 120 130 140 150 KFSRIHCDIF VTLDVMMCTA SILNLCAISI DRYTAVAMPM LYNTRYSSKR 160 170 180 190 200 RVTVMISIVW VLSFTISCPL LFGLNNADQN ECIIANPAFV VYSSIVSFYV 210 220 230 240 250 PFIVTLLVYI KIYIVLRRRR KRSQQKEKKA TQMLAIVLGV FIICWLPFFI 260 270 280 290 300 THILNIHCDC NIPPVLYSAF TWLGYVNSAV NPIIYTTFNI EFRKAFLKIL HC
Scientific name: Homo sapiens
Is this protein a mutant? True
Mutations:
Residue 363: From L to -
Residue 362: From K to -
Residue 361: From R to -
Residue 360: From R to -
Residue 359: From S to -
Residue 358: From M to -
Residue 357: From T to -
Residue 356: From K to -
Residue 355: From L to -
Residue 354: From S to -
Residue 353: From T to -
Residue 352: From R to -
Residue 351: From T to -
Residue 350: From K to -
Residue 349: From G to -
Residue 348: From N to -
Residue 347: From P to -
Residue 346: From M to -
Residue 345: From T to -
Residue 344: From Q to -
Residue 343: From I to -
Residue 342: From E to -
Residue 341: From F to -
Residue 340: From I to -
Residue 339: From K to -
Residue 338: From A to -
Residue 337: From I to -
Residue 336: From K to -
Residue 335: From P to -
Residue 334: From H to -
Residue 333: From D to -
Residue 332: From K to -
Residue 331: From A to -
Residue 330: From H to -
Residue 329: From G to -
Residue 328: From N to -
Residue 327: From K to -
Residue 326: From E to -
Residue 325: From P to -
Residue 324: From K to -
Residue 323: From A to -
Residue 322: From P to -
Residue 321: From S to -
Residue 320: From D to -
Residue 319: From P to -
Residue 318: From T to -
Residue 317: From S to -
Residue 316: From H to -
Residue 315: From L to -
Residue 314: From G to -
Residue 313: From H to -
Residue 312: From H to -
Residue 311: From S to -
Residue 310: From P to -
Residue 309: From D to -
Residue 308: From P to -
Residue 307: From L to -
Residue 306: From T to -
Residue 305: From L to -
Residue 304: From Q to -
Residue 303: From H to -
Residue 302: From H to -
Residue 301: From S to -
Residue 300: From P to -
Residue 299: From P to -
Residue 298: From I to -
Residue 297: From P to -
Residue 296: From S to -
Residue 295: From Y to -
Residue 294: From R to -
Residue 293: From T to -
Residue 292: From R to -
Residue 291: From E to -
Residue 290: From P to -
Residue 289: From P to -
Residue 288: From S to -
Residue 287: From T to -
Residue 286: From S to -
Residue 285: From S to -
Residue 284: From L to -
Residue 283: From M to -
Residue 282: From E to -
Residue 281: From M to -
Residue 280: From E to -
Residue 279: From L to -
Residue 278: From E to -
Residue 277: From Q to -
Residue 276: From A to -
Residue 275: From R to -
Residue 274: From R to -
Residue 273: From A to -
Residue 272: From A to -
Residue 271: From E to -
Residue 270: From V to -
Residue 269: From R to -
Residue 268: From R to -
Residue 267: From R to -
Residue 266: From N to -
Residue 265: From V to -
Residue 264: From P to -
Residue 263: From F to -
Residue 262: From S to -
Residue 261: From G to -
Residue 260: From N to -
Residue 259: From S to -
Residue 258: From K to -
Residue 257: From M to -
Residue 256: From I to -
Residue 255: From V to -
Residue 254: From T to -
Residue 253: From C to -
Residue 252: From L to -
Residue 251: From K to -
Residue 250: From M to -
Residue 249: From D to -
Residue 248: From E to -
Residue 247: From P to -
Residue 246: From H to -
Residue 245: From T to -
Residue 244: From C to -
Residue 243: From N to -
Residue 242: From G to -
Residue 241: From K to -
Residue 240: From L to -
Residue 239: From P to -
Residue 238: From A to -
Residue 237: From R to -
Residue 236: From L to -
Residue 235: From H to -
Residue 234: From A to -
Residue 233: From R to -
Residue 232: From F to -
Residue 231: From A to -
Residue 230: From R to -
Residue 229: From S to -
Residue 228: From S to -
Residue 227: From R to -
Residue 226: From K to -
Residue 225: From T to -
Residue 224: From N to -
Residue 223: From V to -
Alternative names:
D(2) dopamine receptor
Corresponding Cannonical Protein:
Protein ID: 90
You can find this protein in the following complex structures:
Complex Structure ID: 268 Complex Structure ID: 270 Complex Structure ID: 271 Complex Structure ID: 265 Complex Structure ID: 266 Complex Structure ID: 264 Complex Structure ID: 263 Complex Structure ID: 269 Complex Structure ID: 267 Complex Structure ID: 1255
References in which this protein is mentioned:
The UniProt Consortium. 2014. UniProt: a hub for protein information. Nucleic Acids Research 43 (None). doi: https://doi.org/10.1093/nar/gku989. Available in: Pubmed Link
Marie-Lise Jobin, Véronique De Smedt-Peyrusse, Fabien Ducrocq, Rim Baccouch, Asma Oummadi, Maria Hauge Pedersen, Brian Medel-Lacruz, Maria-Florencia Angelo, Sandrine Villette, Pierre Van Delft, Laetitia Fouillen, Sébastien Mongrand, Jana Selent, Tarson Tolentino-Cortez, Gabriel Barreda-Gómez, Stéphane Grégoire, Elodie Masson, Thierry Durroux, Jonathan A. Javitch, Ramon Guixà-González, Isabel D. Alves, Pierre Trifilieff. 2023. Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signaling. Molecular Psychiatry (). doi: 10.1038/s41380-022-01928-6. Available in: Pubmed Link