GPCRmd

Protein Information: Frizzled-6

Cannonical Uniprot Accesion Number: O60353

        10         20         30         40         50
DIGFWCPRHL KTSGGQGYKF LGIDQCAPPC PNMYFKSDEL EFAKSFIGTV 
        60         70         80         90        100
SIFCLCATLF TFLTFLIDVR RFRYPERPII YYSVCYSIVS LMYFIGFLLG 
       110        120        130        140        150
DSTACNKADE KLELGDTVVL GSQNKACTVL FMLLYFFTMA GTVWWVILTI 
       160        170        180        190        200
TWFLAAGRKW SCEAIEQKAV WFHAVAWGTP GFLTVMLLAM NKVEGDNISG 
       210        220        230        240        250
VCFVGLYDLD ASRYFVLLPL CLCVFVGLSL LLAGIISLNH VRQVIQHDGR 
       260        270        280        290        300
NQEKLKKFMI RIGVFSGLYL VFLVTLLGCY VYEQVNRITW EITWVSDHCR 
       310        320        330        340        350
QYHIPCPYQA KAKARPELAL FMIKYLMTLI VGISAVFWVG SKKTCTEWAG 
       
FFKRNR

Scientific name: Homo sapiens

Is this protein a mutant? True

Mutations:

Residue 427: From P to F

Corresponding Cannonical Protein:

Protein ID: 250

You can find this protein in the following complex structures:

Complex Structure ID: 251

References in which this protein is mentioned:

Ainoleena Turku; Hannes Schihada; Pawel Kozielewicz; Carl-Fredrik Bowin; Gunnar Schulte. 2021. Residue 6.43 defines receptor function in class F GPCRs. Nature communications 12 (1). doi: 10.1038/s41467-021-24004-z. Available in: Pubmed Link