Protein Information: Frizzled-6
Cannonical Uniprot Accesion Number: O60353
10 20 30 40 50
DIGFWCPRHL KTSGGQGYKF LGIDQCAPPC PNMYFKSDEL EFAKSFIGTV
60 70 80 90 100
SIFCLCATLF TFLTFLIDVR RFRYPERPII YYSVCYSIVS LMYFIGFLLG
110 120 130 140 150
DSTACNKADE KLELGDTVVL GSQNKACTVL FMLLYFFTMA GTVWWVILTI
160 170 180 190 200
TWFLAAGRKW SCEAIEQKAV WFHAVAWGTP GFLTVMLLAM NKVEGDNISG
210 220 230 240 250
VCFVGLYDLD ASRYFVLLPL CLCVFVGLSL LLAGIISLNH VRQVIQHDGR
260 270 280 290 300
NQEKLKKFMI RIGVFSGLYL VFLVTLLGCY VYEQVNRITW EITWVSDHCR
310 320 330 340 350
QYHIPCPYQA KAKARPELAL FMIKYLMTLI VGISAVFWVG SKKTCTEWAG
FFKRNR
Scientific name: Homo sapiens
Is this protein a mutant? True
Mutations:
Residue 427: From P to F
Corresponding Cannonical Protein:
Protein ID: 250
You can find this protein in the following complex structures:
Complex Structure ID: 251
References in which this protein is mentioned:
Ainoleena Turku; Hannes Schihada; Pawel Kozielewicz; Carl-Fredrik Bowin; Gunnar Schulte. 2021. Residue 6.43 defines receptor function in class F GPCRs. Nature communications 12 (1). doi: 10.1038/s41467-021-24004-z. Available in: Pubmed Link
