Protein Information: Frizzled-6
Cannonical Uniprot Accesion Number: O60353
10 20 30 40 50
MEMFTFLLTC IFLPLLRGHS LFTCEPITVP RCMKMAYNMT FFPNLMGHYD
60 70 80 90 100
QSIAAVEMEH FLPLANLECS PNIETFLCKA FVPTCIEQIH VVPPCRKLCE
110 120 130 140 150
KVYSDCKKLI DTFGIRWPEE LECDRLQYCD ETVPVTFDPH TEFLGPQKKT
160 170 180 190 200
EQVQRDIGFW CPRHLKTSGG QGYKFLGIDQ CAPPCPNMYF KSDELEFAKS
210 220 230 240 250
FIGTVSIFCL CATLFTFLTF LIDVRRFRYP ERPIIYYSVC YSIVSLMYFI
260 270 280 290 300
GFLLGDSTAC NKADEKLELG DTVVLGSQNK ACTVLFMLLY FFTMAGTVWW
310 320 330 340 350
VILTITWFLA AGRKWSCEAI EQKAVWFHAV AWGTPGFLTV MLLAMNKVEG
360 370 380 390 400
DNISGVCFVG LYDLDASRYF VLLPLCLCVF VGLSLLLAGI ISLNHVRQVI
410 420 430 440 450
QHDGRNQEKL KKFMIRIGVF SGLYLVPLVT LLGCYVYEQV NRITWEITWV
460 470 480 490 500
SDHCRQYHIP CPYQAKAKAR PELALFMIKY LMTLIVGISA VFWVGSKKTC
510 520 530 540 550
TEWAGFFKRN RKRDPISESR RVLQESCEFF LKHNSKVKHK KKHYKPSSHK
560 570 580 590 600
LKVISKSMGT STGATANHGT SAVAITSHDY LGQETLTEIQ TSPETSMREV
610 620 630 640 650
KADGASTPRL REQDCGEPAS PAASISRLSG EQVDGKGQAG SVSESARSEG
660 670 680 690 700
RISPKSDITD TGLAQSNNLQ VPSSSEPSSL KGSTSLLVHP VSGVRKEQGG
GCHSDT
Scientific name: Homo sapiens
Is this protein a mutant? False
Alternative names:
Fz-6
hFz6
Corresponding Cannonical Protein:
Protein ID: 250
You can find this protein in the following complex structures:
Complex Structure ID: 250 Complex Structure ID: 252 Complex Structure ID: 208 Complex Structure ID: 204 Complex Structure ID: 253
References in which this protein is mentioned:
Kozielewicz P, Turku A, Bowin C-F, Petersen J, Valnohova J, Consuelo Alonso Cañizal M, Ono Y, Inoue A, Hoffmann C, Schulte G. 2020. Structural insight into small molecule action on Frizzleds. Nature communications 1 (11). doi: 10.1038/s41467-019-14149-3. Available in: Pubmed Link
Ainoleena Turku; Hannes Schihada; Pawel Kozielewicz; Carl-Fredrik Bowin; Gunnar Schulte. 2021. Residue 6.43 defines receptor function in class F GPCRs. Nature communications 12 (1). doi: 10.1038/s41467-021-24004-z. Available in: Pubmed Link
