Protein Information: Smoothened homolog
Cannonical Uniprot Accesion Number: Q99835
10 20 30 40 50
SGQCEVPLVR TDNPKSWYED VEGCGIQCQN PLFTEAEHQD MHSYIAAFGA
60 70 80 90 100
VTGLCTLFTL ATFVADWRNS NRYPAVILFY VNACFFVGSI GWLAQFMDGA
110 120 130 140 150
RREIVCRADG TMRLGEPTSN ETLSCVIIFV IVYYALMAGV VWFVVLTYAW
160 170 180 190 200
HTSFKALGTT YQPLSGKTSY FHLLTWSLPF VLTVAILAVA QVDGDSVSGI
210 220 230 240 250
CFVGYKNYRY RAGFVLAPIG LVLIVGGYFL IRGVMTLFSI KSNHPGLLSE
260 270 280 290 300
KAASKINETM LRLGIFGFLA FGPVLITFSC HFYDFFNQAE WERSFRDYVL
310 320 330 340 350
CQANVTIGLP TKQPIPDCEI KNRPSLLVEK INLFAMFGTG IAMSTWVWTK
360
ATLLIWRRTW CRLT
Scientific name: Homo sapiens
Is this protein a mutant? True
Mutations:
Residue 462: From F to P
Corresponding Cannonical Protein:
Protein ID: 185
You can find this protein in the following complex structures:
Complex Structure ID: 249
References in which this protein is mentioned:
Ainoleena Turku; Hannes Schihada; Pawel Kozielewicz; Carl-Fredrik Bowin; Gunnar Schulte. 2021. Residue 6.43 defines receptor function in class F GPCRs. Nature communications 12 (1). doi: 10.1038/s41467-021-24004-z. Available in: Pubmed Link
