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Protein Information: 5-hydroxytryptamine receptor 1A

Cannonical Uniprot Accesion Number: P08908

        10         20         30         40         50
MDVLSPGQGN NTTSPPAPFE TGGNTTGISD VTVSYQVITS LLLGTLIFCA 
        60         70         80         90        100
VLGNACVVAA IALERSLQNV ANYLIGSLAV TDLMVSVLVL PMAALYQVLN 
       110        120        130        140        150
KWTLGQVTCD LFIALDVLCC TSSILHLCAI ALDRYWAITD PIDYVNKRTP 
       160        170        180        190        200
RRAAALISLT WLIGFLISIP PMLGWRTPED RSDPDACTIS KDHGYTIYST 
       210        220        230        240        250
FGAFYIPLLL MLVLYGRIFR AARFRIRKTV KKVEKTGAAE AKRKMALARE 
       260        270        280        290        300
RKTVKTLGII MGTFILCWLP FFIVALVLPF CESSCHMPTL LGAIINWLGY 
       310        320        330    
SNSLLNPVIY AYFNKDFQNA FKKIIKCKFC RQ

Scientific name: Homo sapiens


Is this protein a mutant? False


Mutations:


Residue 239: From D to -

Residue 240: From T to -

Residue 241: From R to -

Residue 242: From H to -

Residue 243: From G to -

Residue 244: From A to -

Residue 245: From S to -

Residue 246: From P to -

Residue 247: From A to -

Residue 248: From P to -

Residue 249: From Q to -

Residue 250: From P to -

Residue 251: From K to -

Residue 252: From K to -

Residue 253: From S to -

Residue 254: From V to -

Residue 255: From N to -

Residue 256: From G to -

Residue 257: From E to -

Residue 258: From S to -

Residue 259: From G to -

Residue 260: From S to -

Residue 261: From R to -

Residue 262: From N to -

Residue 263: From W to -

Residue 264: From R to -

Residue 265: From L to -

Residue 266: From G to -

Residue 267: From V to -

Residue 268: From E to -

Residue 269: From S to -

Residue 270: From K to -

Residue 271: From A to -

Residue 272: From G to -

Residue 273: From G to -

Residue 274: From A to -

Residue 275: From L to -

Residue 276: From C to -

Residue 277: From A to -

Residue 278: From N to -

Residue 279: From G to -

Residue 280: From A to -

Residue 281: From V to -

Residue 282: From R to -

Residue 283: From Q to -

Residue 284: From G to -

Residue 285: From D to -

Residue 286: From D to -

Residue 287: From G to -

Residue 288: From A to -

Residue 289: From A to -

Residue 290: From L to -

Residue 291: From E to -

Residue 292: From V to -

Residue 293: From I to -

Residue 294: From E to -

Residue 295: From V to -

Residue 296: From H to -

Residue 297: From R to -

Residue 298: From V to -

Residue 299: From G to -

Residue 300: From N to -

Residue 301: From S to -

Residue 302: From K to -

Residue 303: From E to -

Residue 304: From H to -

Residue 305: From L to -

Residue 306: From P to -

Residue 307: From L to -

Residue 308: From P to -

Residue 309: From S to -

Residue 310: From E to -

Residue 311: From A to -

Residue 312: From G to -

Residue 313: From P to -

Residue 314: From T to -

Residue 315: From P to -

Residue 316: From C to -

Residue 317: From A to -

Residue 318: From P to -

Residue 319: From A to -

Residue 320: From S to -

Residue 321: From F to -

Residue 322: From E to -

Residue 323: From R to -

Residue 324: From K to -

Residue 325: From N to -

Residue 326: From E to -

Residue 327: From R to -

Residue 328: From N to -

Alternative names:


  • 5-HT-1A

  • 5-HT1A

  • G-21

  • Serotonin receptor 1A


Corresponding Cannonical Protein:


Protein ID: 2258

You can find this protein in the following complex structures:


Complex Structure ID: 2097

References in which this protein is mentioned:


Kumar, G. Aditya and Sarkar, Parijat and Stepniewski, Tomasz Maciej and Jafurulla, Md. and Singh, Shishu Pal and Selent, Jana and Chattopadhyay, Amitabha. 2021. A molecular sensor for cholesterol in the human serotonin 1A receptor. Science Advances 7 (30). doi: 10.1126/sciadv.abh2922. Available in: Pubmed Link

SUPPORTED BY

ERNEST (COST Action CA18133)

GLISTEN (COST Action CM1207)

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