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Publications

Gareri, Clarice and Pfeiffer, Conrad T. and Jiang, Xue and Paulo, Joao A. and Gygi, Steven P. and Pham, Uyen and Chundi, Anand and Wingler, Laura M. and Staus, Dean P. and Stepniewski, Tomasz Maciej and Selent, Jana and Lucero, Emilio Y. and Grogan, Alyssa and Rajagopal, Sudarshan and Rockman, Howard A.. 2024. Phosphorylation patterns in the AT1R C-terminal tail specify distinct downstream signaling pathways. Science Signaling 17 (849). doi: 10.1126/scisignal.adk5736. (http://dx.doi.org/10.1126/scisignal.adk5736)



Dynamic id Receptor Model name Uniprot entry name Uniprot ID Family Class PDB ID State Species Model type Source type Ligand(s) Num. of atoms Membrane composition Accum. sim. time (µs) Software Force field Submitted by
2052 Beta-arrestin-2 AT1 receptot/B-arr2 complex PROX + MID + DIST phosphorylat... P29067 None 6K3F None Rattus norvegicus Complex X-ray Beta-arrestin-2 6004 3.00 Acemd 3.0 Charmm 36M Tomasz Stepniewski, IMIM
2053 Beta-arrestin-2 At1 receptot/b-arr2 complex mid + dist phosphorylation P29067 None 6K3F None Rattus norvegicus Complex X-ray Beta-arrestin-2 5988 3.00 Acemd 3.0 Charmm 36M Tomasz Stepniewski, IMIM
2054 Type-1 angiotensin ii receptor At1 receptot/b-arr2 complex PROX + DIST phosphorylation Q53YY0 P29067 None 6K3F None Homo sapiens Complex X-ray Beta-arrestin-2 Type-1 angiotensin ii receptor 5988 3.00 Acemd 3.0 Charmm 36M Tomasz Stepniewski, IMIM

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