Publications
Marie-Lise Jobin, Véronique De Smedt-Peyrusse, Fabien Ducrocq, Rim Baccouch, Asma Oummadi, Maria Hauge Pedersen, Brian Medel-Lacruz, Maria-Florencia Angelo, Sandrine Villette, Pierre Van Delft, Laetitia Fouillen, Sébastien Mongrand, Jana Selent, Tarson Tolentino-Cortez, Gabriel Barreda-Gómez, Stéphane Grégoire, Elodie Masson, Thierry Durroux, Jonathan A. Javitch, Ramon Guixà-González, Isabel D. Alves, Pierre Trifilieff. 2023. Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signaling. Molecular Psychiatry. doi: 10.1038/s41380-022-01928-6.
| Receptor | Uniprot entry name | Uniprot ID | Family | Class | PDB ID | State | Species | Model type | Ligand(s) | Model name | Num. of atoms | Membrane composition | Accum. sim. time (µs) | Software | Force field | Submitted by | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| View | D(2) dopamine receptor | drd2_human | P14416 | Dopamine receptors | A | 6CM4 | Inactive | Homo sapiens | Apoform | Dopamine D2 receptor | 43025 | PSM DOPC DPPC DSPC OMEG CHL1 | 4.00 | ACEMD 3.3.0 | CHARMM CHARMM36m | Ramon Guixà-González, Paul Scherrer Institut | Report | |
| View | D(2) dopamine receptor | drd2_human | P14416 | Dopamine receptors | A | 6CM4 | Inactive | Homo sapiens | Apoform | Dopamine d2 receptor (apoform) | 42931 | SDPC PSM DOPC DSPC DPPC CHL1 | 3.73 | ACEMD 3.3.0 | CHARMM CHARMM36m | Ramon Guixà-González, Paul Scherrer Institut | Report | |
| View | Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 | drd2_human | P62873 | Dopamine receptors | A | 6VMS | Active | Homo sapiens | Complex | Aripiprazole | Dopamine D2 receptor in complex with aripiprazole | 42983 | SDPC PSM DOPC DSPC DPPC CHL1 | 4.00 | ACEMD 3.3.0 | CHARMM CHARMM36m | Ramon Guixà-González, Paul Scherrer Institut | Report |
| View | Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 | drd2_human | P62873 | Dopamine receptors | A | 6VMS | Active | Homo sapiens | Complex | Dopamine | Dopamine D2 receptor in complex with dopamine | 43136 | SDPC PSM DOPC DSPC DPPC CHL1 | 4.17 | ACEMD 3.3.0 | CHARMM CHARMM36m | Ramon Guixà-González, Paul Scherrer Institut | Report |
| View | D(2) dopamine receptor | drd2_human | P14416 | Dopamine receptors | A | 6CM4 | Inactive | Homo sapiens | Apoform | Dopamine D2 receptor (apoform) | 42802 | SDPC SM18 DOPC DSPC DPPC CHL1 | 3.61 | ACEMD 3.3.0 | CHARMM CHARMM36m | Ramon Guixà-González, Paul Scherrer Institut | Report |
