Scientific name: Homo sapiens

Is this protein a mutant? True

Mutations:

Residue 1: From M to -

Residue 2: From A to -

Residue 3: From L to -

Residue 4: From S to -

Residue 5: From Y to -

Residue 6: From R to -

Residue 7: From V to -

Residue 8: From S to -

Residue 9: From E to -

Residue 10: From L to -

Residue 11: From Q to -

Residue 12: From S to -

Residue 13: From T to -

Residue 14: From I to -

Residue 15: From P to -

Residue 16: From E to -

Residue 17: From H to -

Residue 18: From I to -

Residue 19: From L to -

Residue 20: From Q to -

Residue 21: From S to -

Residue 22: From T to -

Residue 23: From F to -

Residue 24: From V to -

Residue 25: From H to -

Residue 26: From V to -

Residue 27: From I to -

Residue 28: From S to -

Residue 29: From S to -

Residue 30: From N to -

Residue 31: From W to -

Residue 32: From S to -

Residue 33: From G to -

Residue 34: From L to -

Residue 35: From Q to -

Residue 36: From T to -

Residue 37: From E to -

Residue 38: From S to -

Residue 39: From I to -

Residue 40: From P to -

Residue 144: From M to W

Residue 249: From Y to -

Residue 250: From L to -

Residue 251: From V to -

Residue 252: From K to -

Residue 253: From N to -

Residue 254: From K to -

Residue 255: From P to -

Residue 256: From P to -

Residue 257: From Q to -

Residue 258: From R to -

Residue 259: From L to -

Residue 260: From T to -

Residue 261: From W to -

Residue 262: From L to -

Residue 263: From T to -

Residue 264: From V to -

Residue 265: From S to -

Residue 266: From T to -

Residue 267: From V to -

Residue 268: From F to -

Residue 269: From Q to -

Residue 270: From R to -

Residue 271: From D to -

Residue 272: From E to -

Residue 273: From T to -

Residue 274: From P to -

Residue 275: From C to -

Residue 276: From S to -

Residue 277: From S to -

Residue 278: From P to -

Residue 279: From E to -

Residue 280: From K to -

Residue 281: From V to -

Residue 282: From A to -

Residue 283: From M to -

Residue 284: From L to -

Residue 285: From D to -

Residue 286: From G to -

Residue 287: From S to -

Residue 288: From R to -

Residue 289: From K to -

Residue 290: From D to -

Residue 291: From K to -

Residue 292: From A to -

Residue 293: From L to -

Residue 294: From P to -

Residue 295: From N to -

Residue 296: From S to -

Residue 297: From G to -

Residue 298: From D to -

Residue 299: From E to -

Residue 300: From T to -

Residue 301: From L to -

Residue 302: From M to -

Residue 303: From R to -

Residue 304: From R to -

Residue 305: From T to -

Residue 306: From S to -

Residue 307: From T to -

Residue 308: From I to -

Residue 309: From G to -

Residue 310: From K to -

Residue 311: From K to -

Residue 312: From S to -

Residue 313: From - to A

Residue 314: From - to D

Residue 315: From - to L

Residue 316: From - to E

Residue 317: From - to D

Residue 318: From - to N

Residue 319: From - to W

Residue 320: From - to E

Residue 321: From - to T

Residue 322: From - to L

Residue 323: From - to N

Residue 324: From - to D

Residue 325: From - to N

Residue 326: From - to L

Residue 327: From - to K

Residue 328: From - to V

Residue 329: From - to I

Residue 330: From - to E

Residue 331: From - to K

Residue 332: From - to A

Residue 333: From - to D

Residue 334: From - to N

Residue 335: From - to A

Residue 336: From - to A

Residue 337: From - to Q

Residue 338: From - to V

Residue 339: From - to K

Residue 340: From - to D

Residue 341: From - to A

Residue 342: From - to L

Residue 343: From - to T

Residue 344: From - to K

Residue 345: From - to M

Residue 346: From - to R

Residue 347: From - to A

Residue 348: From - to A

Residue 349: From - to A

Residue 350: From - to L

Residue 351: From - to D

Residue 352: From - to A

Residue 353: From - to Q

Residue 354: From - to K

Residue 355: From - to A

Residue 356: From - to T

Residue 357: From - to P

Residue 358: From - to P

Residue 359: From - to K

Residue 360: From - to L

Residue 361: From - to E

Residue 362: From - to D

Residue 363: From - to K

Residue 364: From - to S

Residue 365: From - to P

Residue 366: From - to D

Residue 367: From - to S

Residue 368: From - to P

Residue 369: From - to E

Residue 370: From - to M

Residue 371: From - to K

Residue 372: From - to D

Residue 373: From - to F

Residue 374: From - to R

Residue 375: From - to H

Residue 376: From - to G

Residue 377: From - to F

Residue 378: From - to D

Residue 379: From - to I

Residue 380: From - to L

Residue 381: From - to V

Residue 382: From - to G

Residue 383: From - to Q

Residue 384: From - to I

Residue 385: From - to D

Residue 386: From - to D

Residue 387: From - to A

Residue 388: From - to L

Residue 389: From - to K

Residue 390: From - to L

Residue 391: From - to A

Residue 392: From - to N

Residue 393: From - to E

Residue 394: From - to G

Residue 395: From - to K

Residue 396: From - to V

Residue 397: From - to K

Residue 398: From - to E

Residue 399: From - to A

Residue 400: From - to Q

Residue 401: From - to A

Residue 402: From - to A

Residue 403: From - to A

Residue 404: From - to E

Residue 405: From - to Q

Residue 406: From - to L

Residue 407: From - to K

Residue 408: From - to T

Residue 409: From - to T

Residue 410: From - to R

Residue 411: From - to N

Residue 412: From - to A

Residue 413: From - to Y

Residue 414: From - to I

Residue 415: From - to Q

Residue 416: From - to K

Residue 417: From - to Y

Residue 418: From - to L

Residue 507: From A to -

Residue 508: From T to -

Residue 509: From K to -

Residue 510: From S to -

Residue 511: From V to -

Residue 512: From K to -

Residue 513: From T to -

Residue 514: From L to -

Residue 515: From R to -

Residue 516: From K to -

Residue 517: From R to -

Residue 518: From S to -

Residue 519: From S to -

Residue 520: From K to -

Residue 521: From I to -

Residue 522: From Y to -

Residue 523: From F to -

Residue 524: From R to -

Residue 525: From N to -

Residue 526: From P to -

Residue 527: From M to -

Residue 528: From A to -

Residue 529: From E to -

Residue 530: From N to -

Residue 531: From S to -

Residue 532: From K to -

Residue 533: From F to -

Residue 534: From F to -

Residue 535: From K to -

Residue 536: From K to -

Residue 537: From H to -

Residue 538: From G to -

Residue 539: From I to -

Residue 540: From R to -

Residue 541: From N to -

Residue 542: From G to -

Residue 543: From I to -

Residue 544: From N to -

Residue 545: From P to -

Residue 546: From A to -

Residue 547: From M to -

Residue 548: From Y to -

Residue 549: From Q to -

Residue 550: From S to -

Residue 551: From P to -

Residue 552: From M to -

Residue 553: From R to -

Residue 554: From L to -

Residue 555: From R to -

Residue 556: From S to -

Residue 557: From S to -

Residue 558: From T to -

Residue 559: From I to -

Residue 560: From Q to -

Residue 561: From S to -

Residue 562: From S to -

Residue 563: From S to -

Residue 564: From I to -

Residue 565: From I to -

Residue 566: From L to -

Residue 567: From L to -

Residue 568: From D to -

Residue 569: From T to -

Residue 570: From L to -

Residue 571: From L to -

Residue 572: From L to -

Residue 573: From T to -

Residue 574: From E to -

Residue 575: From N to -

Residue 576: From E to -

Residue 577: From G to -

Residue 578: From D to -

Residue 579: From K to -

Residue 580: From T to -

Residue 581: From E to -

Residue 582: From E to -

Residue 583: From Q to -

Residue 584: From V to -

Residue 585: From S to -

Residue 586: From Y to -

Residue 587: From V to -

Corresponding Cannonical Protein:

Protein ID: 109

You can find this protein in the following complex structures:

Complex Structure ID: 215 Complex Structure ID: 219 Complex Structure ID: 220 Complex Structure ID: 221 Complex Structure ID: 217 Complex Structure ID: 218

References in which this protein is mentioned:

Peters, Brandon L. and Deng, Jinxia and Ferguson, Andrew L., Garriga, Pere. 2020. Free energy calculations of the functional selectivity of 5-HT2B G protein-coupled receptor. PLOS ONE 15 (12). doi: 10.1371/journal.pone.0243313. Available in: Pubmed Link