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Protein Information: Frizzled-7

Cannonical Uniprot Accesion Number: O75084

        10         20         30         40         50
MRDPGAAAPL SSLGLCALVL ALLGALSAGA GAQPYHGEKG ISVPDHGFCQ 
        60         70         80         90        100
PISIPLCTDI AYNQTILPNL LGHTNQEDAG LEVHQFYPLV KVQCSPELRF 
       110        120        130        140        150
FLCSMYAPVC TVLDQAIPPC RSLCERARQG CEALMNKFGF QWPERLRCEN 
       160        170        180        190        200
FPVHGAGEIC VGQNTSDGSG GPGGGPTAYP TAPYLPDLPF TALPPGASDG 
       210        220        230        240        250
RGRPAFPFSC PRQLKVPPYL GYRFLGERDC GAPCEPGRAN GLMYFKEEER 
       260        270        280        290        300
RFARLWVGVW SVLCCASTLF TVLTYLVDMR RFSYPERPII FLSGCYFMVA 
       310        320        330        340        350
VAHVAGFLLE DRAVCVERFS DDGYRTVAQG TKKEGCTILF MVLYFFGMAS 
       360        370        380        390        400
SIWWVILSLT WFLAAGMKWG HEAIEANSQY FHLAAWAVPA VKTITILAMG 
       410        420        430        440        450
QVDGDLLSGV CYVGLSSVDA LRGFVLAPLF VYLFIGTSFL LAGFVSLFRI 
       460        470        480        490        500
RTIMKHDGTK TEKLEKLMVR IGVFSVLYTV PATIVLACYF YEQAFREHWE 
       510        520        530        540        550
RTWLLQTCKS YAVPCPPGHF PPMSPDFTVF MIKYLMTMIV GITTGFWIWS 
       560        570      
GKTLQSWRRF YHRLSHSSKG ETAV

Scientific name: Homo sapiens


Is this protein a mutant? False


Alternative names:


  • Fz-7

  • FzE3

  • hFz7


Corresponding Cannonical Protein:


Protein ID: 280

You can find this protein in the following complex structures:


Complex Structure ID: 2081

References in which this protein is mentioned:


Bous, Julien and Kinsolving, Julia and Gratz, Lukas and Scharf, Magdalena M. and Voss, Jan Hendrik and Selcuk, Berkay and Adebali, Ogun and Schulte, Gunnar. 2024. Structural basis of frizzled 7 activation and allosteric regulation. Nature Communications 15 (1). doi: 10.1038/s41467-024-51664-4. Available in: Pubmed Link

SUPPORTED BY

ERNEST (COST Action CA18133)

GLISTEN (COST Action CM1207)

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