Free cookie consent management tool by TermsFeed GPCRmd
× Due to a recent server update, this page will be slow for the next 1-2 hours. We apologize for any inconvenience this may cause.

Protein Information: Guanine nucleotide-binding protein G(i) subunit alpha-1

Cannonical Uniprot Accesion Number: P63096

        10         20         30         40         50
MGCTLSAEDK AAVERSKMID RNLREDGEKA AREVKLLLLG AGESGKSTIV 
        60         70         80         90        100
KQMKTGIVET HFTFKDLHFK MFDVGGQRSE RKKWIHCFEG VTAIIFCVAL 
       110        120        130        140        150
SDYDLMNRMH ESMKLFDSIC NNKWFTDTSI ILFLNKKDLF EEKIKKSPLT 
       160        170        180        190        200
ICYPEYAGSN TYEEAAAYIQ CQFEDLNKRK DTKEIYTHFT CATDTKNVQF 
       210        220  
VFDAVTDVII KNNLKDCGLF 

Scientific name: Homo sapiens


Is this protein a mutant? True


Alternative names:


  • Adenylate cyclase-inhibiting G alpha protein


Corresponding Cannonical Protein:


Protein ID: 1154

You can find this protein in the following complex structures:


Complex Structure ID: 1164 Complex Structure ID: 1193 Complex Structure ID: 1194 Complex Structure ID: 1264 Complex Structure ID: 1265 Complex Structure ID: 1266 Complex Structure ID: 1267 Complex Structure ID: 1217 Complex Structure ID: 1199 Complex Structure ID: 1203 Complex Structure ID: 1274 Complex Structure ID: 1205 Complex Structure ID: 1206 Complex Structure ID: 1273 Complex Structure ID: 1268 Complex Structure ID: 1217 Complex Structure ID: 1269

References in which this protein is mentioned:


Manbir Sandhu, Aaron Cho, Ning Ma, Elizaveta Mukhaleva, Yoon Namkung, Sangbae Lee, Soumadwip Ghosh, John H. Lee, David E. Gloriam, Stéphane A. Laporte, M. Madan Babu, Nagarajan Vaidehi. 2022. Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity. Nature Communications (). doi: 10.1038/s41467-022-34055-5. Available in: Pubmed Link

SUPPORTED BY

ERNEST (COST Action CA18133)

GLISTEN (COST Action CM1207)

GPCRForum