Complex Information
Proteins used in this complex:
Adenosine receptor A2a (Homo sapiens)
Orthosteric ligand(s) in this complex:
Kd values:
Kd according to BindingDB: 0.22 nM Original page
Kd according to BindingDB: 0.22 nM Original page
Complex structures in which this complex is used:
Complex Structure ID: 41 using Specific State(s): Specific State ID: 4588
Complex Structure ID: 47 using Specific State(s): Specific State ID: 4588
References for this complex:
Slee, DH; Chen, Y; Zhang, X; Moorjani, M; Lanier, MC; Lin, E; Rueter, JK; Williams, JP; Lechner, SM; Markison, S; Malany, S; Santos, M; Gross, RS; Jalali, K; Sai, Y; Zuo, Z; Yang, C; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Saunders, J. 2008. 2-Amino-N-pyrimidin-4-ylacetamides as A2A receptor antagonists: 1. Structure-activity relationships and optimization of heterocyclic substituents.. Journal of medicinal chemistry 51 (6). doi: 10.1021/jm701185v. Available in: Pubmed Link
Slee, DH; Chen, Y; Zhang, X; Moorjani, M; Lanier, MC; Lin, E; Rueter, JK; Williams, JP; Lechner, SM; Markison, S; Malany, S; Santos, M; Gross, RS; Jalali, K; Sai, Y; Zuo, Z; Yang, C; Castro-Palomino, JC; Crespo, MI; Prat, M; Gual, S; Díaz, JL; Saunders, J. 2008. 2-Amino-N-pyrimidin-4-ylacetamides as A2A receptor antagonists: 1. Structure-activity relationships and optimization of heterocyclic substituents.. Journal of medicinal chemistry 51 (6). doi: 10.1021/jm701185v. Available in: Pubmed Link
